Description

(2R,2'R,3R,3'R)-3,3'-Di-tert-Butyl-2,2'-Di(Pentan-3-Yl)-2,2',3,3'-Tetrahydro-4,4'-Bibenzo[D][1,3]Oxaphosphole CAS NO 2213449-78-4 is a sophisticated, chiral organophosphorus compound characterized by its unique binaphthyl-oxaphosphole backbone. This compound is of significant value as a highly selective ligand or catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors where stereochemical control is critical.

Application

• Asymmetric Catalysis: Serving as a chiral ligand for transition metal complexes (e.g., Rh, Pd, Ru) in enantioselective hydrogenation, cross-coupling, and C-H activation reactions.
• Pharmaceutical Intermediate Synthesis: Enabling the stereocontrolled construction of complex active pharmaceutical ingredients (APIs) for novel therapeutics.
• Agrochemical Research: Facilitating the development of enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Potential use in the synthesis of chiral polymers or as a dopant for liquid crystal displays (LCDs) requiring specific optical properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.
• Fine Chemical Production: Used in the pilot and commercial-scale manufacture of specialty flavors, fragrances, and other high-value chiral compounds.

Basic Information

Item	Details
Product Name	(2R,2'R,3R,3'R)-3,3'-Di-tert-Butyl-2,2'-Di(Pentan-3-Yl)-2,2',3,3'-Tetrahydro-4,4'-Bibenzo[D][1,3]Oxaphosphole
CAS No.	2213449-78-4
Molecular Formula	C38H56O2P2
Molecular Weight	606.79 g/mol
Synonyms	(R,R)-3,3'-Di-tert-butyl-2,2'-di(pentan-3-yl)-2,2',3,3'-tetrahydro-4,4'-bibenzo[d][1,3]oxaphosphole; Chiral Binaphthyl Oxaphosphole Ligand; (R,R)-BIBOP Derivative; (2R,2'R,3R,3'R)-BIBOP Ligand Analog; AT-BIBOP; P-Chiral Bidentate Phosphorus Ligand; 3,3'-Di-tert-butyl-2,2'-dipentyl-2,2',3,3'-tetrahydro-4,4'-bi-1,3-benzoxaphosphole (stereoisomer)
EINECS	Contact for details

Quality Control

Our production of this advanced chiral chemical adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including Chiral HPLC, NMR (¹H, ³¹P, ¹³C), and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be purged with inert gas before resealing after each use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.