Description

Benzoic Acid, 4-Amino-3-Fluoro-2-Methyl- is a high-purity, multi-functional aromatic compound that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern, featuring amino, fluoro, and methyl groups on the benzoic acid core, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients. Its precise structure enables modifications that can influence the biological activity, metabolic stability, and physical characteristics of the final target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced functional materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its aromaticity and potential for derivatization.
• Dye & Pigment Manufacturing: Intermediate for producing specialized azo dyes and high-performance pigments, where the amino group is crucial for chromophore formation.
• Polymer Modification: Employed to introduce functional groups into polymer chains, enhancing properties like adhesion, solubility, or thermal resistance in engineering plastics and coatings.
• Chemical Research & Development: A versatile scaffold in medicinal and synthetic chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	Benzoic Acid, 4-Amino-3-Fluoro-2-Methyl-
CAS No.	2167723-59-1
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	4-Amino-3-fluoro-2-methylbenzoic acid; 2-Methyl-4-amino-3-fluorobenzoic acid; 3-Fluoro-4-amino-2-methylbenzoic acid; 4-Amino-3-fluoro-o-toluic acid; 2-Methyl-3-fluoro-4-aminobenzoic acid; Benzoic acid, 4-amino-3-fluoro-2-methyl-; AFMBA
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-Amino-3-Fluoro-2-Methyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) that include results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.