Description

2-Amino-9-((1S,4S)-3,4-Dihydroxy-3-Methyl-2-Methylenecyclopentyl)-8-Methoxy-1,9-Dihydro-6H-Purin-6-One is a high-purity, structurally complex nucleoside analog with significant potential in advanced pharmaceutical research and development. Its unique cyclopentyl-modified purine core makes it a valuable building block for the synthesis of novel therapeutic agents, particularly in antiviral and anticancer applications. This compound is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on next-generation drug discovery.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside analog drugs targeting viral polymerases.
• Antiviral Drug Research: Used in the development of potential therapeutics for a range of viral infections due to its modified purine structure.
• Oncology Research: Serves as a precursor in the creation of investigational antimetabolites and chemotherapeutic agents.
• Biochemical Probe Development: Utilized in medicinal chemistry to study enzyme inhibition and cellular signaling pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial production of active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: A key reagent for universities and research institutes exploring novel nucleoside chemistry and its biological implications.

Basic Information

Product Name	2-Amino-9-((1S,4S)-3,4-Dihydroxy-3-Methyl-2-Methylenecyclopentyl)-8-Methoxy-1,9-Dihydro-6H-Purin-6-One
CAS No.	2165482-46-0
Molecular Formula	C13H17N5O4
Molecular Weight	307.31 g/mol
Synonyms	8-Methoxy-2-amino-9-((1S,4S)-3,4-dihydroxy-3-methyl-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one; (1S,4S)-2-Amino-9-(3,4-dihydroxy-3-methyl-2-methylenecyclopentyl)-8-methoxy-1,9-dihydro-6H-purin-6-one; Cyclopentyl-modified 2-Aminopurine derivative; 2-Amino-9-(3,4-dihydroxy-3-methyl-2-methylidenecyclopentyl)-8-methoxy-1H-purin-6-one; 2165482-46-0; Modified Nucleoside Analog; Purine Nucleoside Mimetic
EINECS	Contact for details

Quality Control

Our 2-Amino-9-((1S,4S)-3,4-Dihydroxy-3-Methyl-2-Methylenecyclopentyl)-8-Methoxy-1,9-Dihydro-6H-Purin-6-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and comprehensive identification and impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.