Description

6-Fluoro-2-Formyl-3-Hydroxybenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique molecular structure, featuring both formyl and carboxylic acid groups on a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, where the fluorine atom enhances bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials where fluorination modifies electronic properties and solubility.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags, photoaffinity labels, and other molecular probes due to its reactive aldehyde and hydroxyl functional groups.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	6-Fluoro-2-Formyl-3-Hydroxybenzoic Acid
CAS No.	2138193-88-9
Molecular Formula	C8H5FO4
Molecular Weight	184.12 g/mol
Synonyms	3-Hydroxy-6-fluoro-2-formylbenzoic acid; 2-Formyl-3-hydroxy-6-fluorobenzoic acid; 6-Fluoro-3-hydroxy-2-formylbenzoic acid; 6-Fluoro-2-carboxy-3-hydroxybenzaldehyde; 2-Carboxy-6-fluoro-3-hydroxybenzaldehyde; 6-Fluorosalicylaldehyde-2-carboxylic acid; Benzoic acid, 6-fluoro-2-formyl-3-hydroxy-
EINECS	Contact for details

Quality Control

Every batch of 6-Fluoro-2-Formyl-3-Hydroxybenzoic Acid is produced and tested under a strict quality management system. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all critical parameters are provided with each shipment and are available for review upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.