Description

3,4-Difluoro-2-((phenylthio)methyl)benzoic acid is a high-value fluorinated benzoic acid derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both fluorine atoms and a phenylthioether moiety, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel ligands in transition metal catalysis and organocatalysis due to its electron-withdrawing and steric properties.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials where fluorinated aromatic units are required.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies in fluorination chemistry and C-S bond formation reactions.

Basic Information

Product Name	3,4-Difluoro-2-((Phenylthio)Methyl)Benzoic Acid
CAS No.	2136287-65-3
Molecular Formula	C14H10F2O2S
Molecular Weight	280.29 g/mol
Synonyms	3,4-Difluoro-2-[(phenylsulfanyl)methyl]benzoic acid; 2-[(Phenylthio)methyl]-3,4-difluorobenzoic acid; Benzoic acid, 3,4-difluoro-2-[(phenylthio)methyl]-; 3,4-Difluoro-2-(phenylthiomethyl)benzoic acid; CAS 2136287-65-3; Difluorophenylthiomethyl benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 3,4-Difluoro-2-((phenylthio)methyl)benzoic acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support development needs with various purity grades, including research and GMP-grade material for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is compatible with strong acid/organic solvent environments but should be kept separate from strong bases and oxidizing agents. Keep the container tightly sealed when not in use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0% (Research Grade) ≥99.0% (High Purity Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.