Description

3,4-Difluoro-2-Methylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, particularly for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing difluoromethylphenyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific fluorinated aromatic systems.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid reagent for palladium-catalyzed carbon-carbon bond formation to create complex biaryl and heterobiaryl compounds.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: A building block for creating novel organic electronic materials, liquid crystals, and polymers with tailored properties.
• Chemical Biology Probes: Used in the development of molecular probes and inhibitors for biochemical and pharmacological research.

Basic Information

Product Name	3,4-Difluoro-2-Methylphenylboronic Acid
CAS No.	2121514-75-6
Molecular Formula	C7H7BF2O2
Molecular Weight	171.94 g/mol
Synonyms	(3,4-Difluoro-2-methylphenyl)boronic acid; 2-Methyl-3,4-difluorophenylboronic acid; B-(3,4-Difluoro-2-methylphenyl)boronic acid; 3,4-Difluoro-o-tolylboronic acid; 2121514-75-6; Boronic acid, B-(3,4-difluoro-2-methylphenyl)-; 2-Methyl-3,4-difluorobenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-2-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.