Description

6-Bromo-2-Fluoro-3-Methylphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific halogenated, fluorinated aromatic structures.
• Material Science Research: Serves as a precursor for creating advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular structure controls performance.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Synthesis: Useful for labeling and modifying biomolecules or creating chemical probes for diagnostic and research applications.

Basic Information

Item	Details
Product Name	6-Bromo-2-Fluoro-3-Methylphenylboronic Acid Pinacol Ester
CAS No.	2121514-68-7
Molecular Formula	C₁₃H₁₇BBrFO₂
Molecular Weight	314.99 g/mol
Synonyms	2-Bromo-6-Fluoro-3-Methylbenzeneboronic Acid Pinacol Ester; (6-Bromo-2-fluoro-3-methylphenyl)boronic Acid Pinacol Ester; 6-Bromo-2-fluoro-3-methylbenzeneboronic Acid Pinacol Ester; Pinacol (6-Bromo-2-fluoro-3-methylphenyl)boronate; 2-Fluoro-6-bromo-3-methylphenylboronic Acid Pinacol Ester; B-(6-Bromo-2-fluoro-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Fluoro-3-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.