Description

4-Bromo-2-Fluoro-3-Iodophenylboronic Acid is a highly functionalized, multi-halogenated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring bromine, fluorine, and iodine substituents on the same aromatic ring, makes it an exceptionally versatile and valuable reagent for constructing complex molecular architectures. This compound is primarily sought after by research scientists and process chemists in the pharmaceutical and agrochemical industries for advanced cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl and heterobiaryl compounds, which are core structures in many drug candidates.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides that require halogenated aromatic motifs for bioactivity.
• Material Science: Employed in the synthesis of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise halogen substitution patterns are crucial.
• Chemical Biology & Probe Development: Acts as a versatile handle for bioconjugation and the creation of molecular probes for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	4-Bromo-2-Fluoro-3-Iodophenylboronic Acid
CAS No.	2121514-50-7
Molecular Formula	C6H4BBrFIO2
Molecular Weight	358.81 g/mol
Synonyms	(4-Bromo-2-fluoro-3-iodophenyl)boronic acid; 4-Bromo-2-fluoro-3-iodobenzeneboronic acid; B-(4-Bromo-2-fluoro-3-iodophenyl)boronic acid; 2121514-50-7; Boronic acid, B-(4-bromo-2-fluoro-3-iodophenyl)-; 4-Br-2-F-3-I-C6H2B(OH)2
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Fluoro-3-Iodophenylboronic Acid is manufactured and tested under a strict quality management system. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.