Description

2-Fluoro-5-Isopropoxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly those requiring fluorinated or substituted phenyl groups.
• Agrochemical Synthesis: Employed in creating advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Material Science Research: A building block for organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	2-Fluoro-5-Isopropoxyphenylboronic Acid Pinacol Ester
CAS No.	2121514-44-9
Molecular Formula	C15H22BFO3
Molecular Weight	280.14 g/mol
Synonyms	2-Fluoro-5-isopropoxybenzeneboronic acid pinacol ester; (2-Fluoro-5-isopropoxyphenyl)boronic acid pinacol ester; 5-Isopropoxy-2-fluorophenylboronic acid pinacol ester; 2-Fluoro-5-(1-methylethoxy)benzeneboronic acid pinacol ester; Boronic acid, B-[2-fluoro-5-(1-methylethoxy)phenyl]-, 1,1,1,1-tetramethyl-2-propanyl ester; Pinacol 2-fluoro-5-isopropoxyphenylboronate; CAS 2121514-44-9
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Isopropoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.