Description

2,6-Difluoro-3-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require the specific difluoromethoxy-phenyl scaffold.
• Liquid Crystal & OLED Materials: Serves as a building block for creating organic electronic materials and liquid crystal compounds due to its stable boronate ester functionality.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and functional materials where the introduction of aryl-boronate groups is required.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and complex molecule construction.
• Ligand & Catalyst Development: Used in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Item	Details
Product Name	2,6-Difluoro-3-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	2121514-34-7
Molecular Formula	C₁₃H₁₇BF₂O₃
Molecular Weight	270.08 g/mol
Synonyms	2,6-Difluoro-3-methoxyphenylboronic acid pinacol ester; (2,6-Difluoro-3-methoxyphenyl)boronic acid pinacol ester; 2,6-Difluoro-3-methoxybenzeneboronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(2,6-difluoro-3-methoxyphenyl)-1,3,2-dioxaborolane; Pinacol (2,6-difluoro-3-methoxyphenyl)boronate; B-(2,6-Difluoro-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.