Description

6-Bromo-3-Chloro-2,4-Difluorophenylboronic Acid is a high-purity, multi-halogenated boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its unique substitution pattern, which enables precise cross-coupling reactions for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic pathways and complex molecule construction.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Bromo-3-Chloro-2,4-Difluorophenylboronic Acid
CAS No.	2121514-24-5
Molecular Formula	C6H3BBrClF2O2
Molecular Weight	271.25 g/mol
Synonyms	(6-Bromo-3-chloro-2,4-difluorophenyl)boronic acid; 2,4-Difluoro-6-bromo-3-chlorophenylboronic acid; 6-Bromo-3-chloro-2,4-difluorobenzeneboronic acid; Boronic acid, B-(6-bromo-3-chloro-2,4-difluorophenyl)-; CAS 2121514-24-5
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloro-2,4-Difluorophenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.