Description

4-Trifluoromethoxy-2-Biphenyl)Boronic Acid is a specialized organoboronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced biological activity and stability.
• Material Science Research: Serves as a precursor for creating advanced organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for transition metal catalysis and in the preparation of boron-containing polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme functions.

Basic Information

Product Name	4-Trifluoromethoxy-2-Biphenyl)Boronic Acid
CAS No.	2121514-20-1
Molecular Formula	C13H10BF3O3
Molecular Weight	282.03 g/mol
Synonyms	[4-(Trifluoromethoxy)[1,1'-biphenyl]-2-yl]boronic acid; 2-Borono-4'-(trifluoromethoxy)biphenyl; (4'-Trifluoromethoxybiphenyl-2-yl)boronic acid; 4'-Trifluoromethoxy-[1,1'-biphenyl]-2-ylboronic acid; 2-(4-Trifluoromethoxyphenyl)phenylboronic acid; B-[4-(Trifluoromethoxy)[1,1'-biphenyl]-2-yl]boronic acid
EINECS	Contact for details

Quality Control

Our production of 4-Trifluoromethoxy-2-Biphenyl)Boronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, typically exceeding 97% (HPLC). Each lot is fully characterized and accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.