Description

2-Fluoro-3-(Morpholinomethyl)Phenylboronic Acid is a specialized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling it to act as a versatile coupling partner in cross-coupling reactions, particularly Suzuki-Miyaura reactions, for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in constructing novel herbicides, fungicides, and insecticides that require the incorporation of fluorine and morpholine motifs for enhanced bioactivity and environmental stability.
• Material Science Research: Building block for creating advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where boronic acids facilitate precise polymer and small-molecule synthesis.
• Chemical Biology & Proteomics: Employed in the development of chemical probes and inhibitors for studying enzyme function and protein-protein interactions.
• Ligand Development for Catalysis: Serves as a precursor for synthesizing novel bidentate or tridentate ligands used in transition metal catalysis.
• Library Synthesis for Drug Discovery: A valuable reagent for parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening (HTS).

Basic Information

Product Name	2-Fluoro-3-(Morpholinomethyl)Phenylboronic Acid
CAS No.	2121514-18-7
Molecular Formula	C11H15BFNO3
Molecular Weight	239.06 g/mol
Synonyms	(2-Fluoro-3-(morpholinomethyl)phenyl)boronic acid; 2-Fluoro-3-morpholin-4-ylmethylbenzeneboronic acid; B-[2-Fluoro-3-(morpholinomethyl)phenyl]boronic acid; 3-(Morpholinomethyl)-2-fluorophenylboronic acid; 2121514-18-7; 2-Fluoro-3-morpholinomethylphenylboronic Acid; Boronic acid, B-[2-fluoro-3-(4-morpholinylmethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-(Morpholinomethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain reliability and batch-to-batch consistency meets the stringent requirements of pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.