Description

3-Chloro-4-Ethoxy-5-Fluorophenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides with specific activity profiles.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and inhibitors for studying biological pathways and protein function.
• Ligand & Catalyst Development: Utilized to construct sophisticated ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring high-fidelity boronic acid components.

Basic Information

Product Name	3-Chloro-4-Ethoxy-5-Fluorophenylboronic Acid
CAS No.	2096334-30-2
Molecular Formula	C8H9BClFO3
Molecular Weight	217.42 g/mol
Synonyms	(3-Chloro-4-ethoxy-5-fluorophenyl)boronic acid; 3-Chloro-4-ethoxy-5-fluorobenzeneboronic acid; B-(3-Chloro-4-ethoxy-5-fluorophenyl)boronic acid; 2096334-30-2; 3-Cl-4-EtO-5-F-PhB(OH)2; 5-Fluoro-3-chloro-4-ethoxybenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Ethoxy-5-Fluorophenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) with full traceability are provided for all shipments, supporting compliance in GMP-oriented applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.