Description

3-Chloro-4-(Cyclopentyloxy)-5-Fluorophenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate for the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl structures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the Suzuki coupling to introduce complex aromatic motifs.
• Material Science Research: Serves as a monomer or building block for creating advanced organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis or as a scaffold for metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring precise boronic acid coupling partners.

Basic Information

Product Name	3-Chloro-4-(Cyclopentyloxy)-5-Fluorophenylboronic Acid
CAS No.	2096334-04-0
Molecular Formula	C11H13BClFO3
Molecular Weight	257.48 g/mol
Synonyms	3-Chloro-4-(cyclopentyloxy)-5-fluorobenzeneboronic acid; (3-Chloro-4-cyclopentyloxy-5-fluorophenyl)boronic acid; 3-Chloro-4-cyclopentyloxy-5-fluorophenylboronic acid; B-[3-Chloro-4-(cyclopentyloxy)-5-fluorophenyl]boronic acid; 2096334-04-0; 3-Chloro-4-cyclopentoxy-5-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(Cyclopentyloxy)-5-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We can support development with custom purity grades, including standards suitable for GMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.