Description

4-Ethoxy-3,5-Difluorophenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. Its value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Critical for synthesizing novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in creating advanced herbicides and fungicides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Material Production: Serves as a building block for fluorine-containing aromatic compounds used in electronic display technologies.
• Polymer Chemistry: Enables the incorporation of difluorinated aryl ether units into specialty polymers for enhanced thermal and chemical stability.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for methodology development and library synthesis.
• Diagnostic Reagent Precursor: Used in the synthesis of fluorinated probes and tags for biochemical assays and imaging.

Basic Information

Product Name	4-Ethoxy-3,5-Difluorophenylboronic Acid
CAS No.	2096333-93-4
Molecular Formula	C8H9BF2O3
Molecular Weight	201.97 g/mol
Synonyms	(4-Ethoxy-3,5-difluorophenyl)boronic acid; 3,5-Difluoro-4-ethoxyphenylboronic acid; B-(4-Ethoxy-3,5-difluorophenyl)boronic acid; 4-Ethoxy-3,5-difluorobenzeneboronic acid; 2096333-93-4; Boronic acid, B-(4-ethoxy-3,5-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3,5-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) with full specification data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.