Description

2,4-Difluoro-5-Isopropoxyphenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in drug discovery for oncology and CNS disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluoro and isopropoxy substituents contribute to enhanced biological activity and stability.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as those for OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to create boronic acid-based sensors and probes for detecting sugars, peroxides, and other analytes.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CMOs for custom synthesis projects requiring specific aryl boronic acid functionalities.

Basic Information

Product Name	2,4-Difluoro-5-Isopropoxyphenylboronic Acid
CAS No.	2096333-88-7
Molecular Formula	C9H11BF2O3
Molecular Weight	216.00 g/mol
Synonyms	(2,4-Difluoro-5-isopropoxyphenyl)boronic acid; 5-Isopropoxy-2,4-difluorophenylboronic acid; 2,4-Difluoro-5-(1-methylethoxy)benzeneboronic acid; Boronic acid, B-(2,4-difluoro-5-isopropoxyphenyl)-; 2096333-88-7; 2,4-Difluoro-5-isopropoxybenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-5-Isopropoxyphenylboronic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent in-house specifications, which are aligned with industry best practices for advanced pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.