Description

Methyl 2-Bromo-6-Fluoro-3-(Trifluoromethyl)Benzoate is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. Its unique combination of bromo, fluoro, and trifluoromethyl substituents makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, anti-cancer agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing character.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form new carbon-carbon bonds.
• Fluorinated Compound Libraries: An essential reagent for medicinal chemistry programs focused on creating fluorinated compound libraries to explore structure-activity relationships (SAR).

Basic Information

Product Name	Methyl 2-Bromo-6-Fluoro-3-(Trifluoromethyl)Benzoate
CAS No.	2090828-24-1
Molecular Formula	C9H5BrF4O2
Molecular Weight	301.04 g/mol
Synonyms	2-Bromo-6-fluoro-3-(trifluoromethyl)benzoic acid methyl ester; Methyl 2-bromo-6-fluoro-α,α,α-trifluoro-m-toluate; Benzoic acid, 2-bromo-6-fluoro-3-(trifluoromethyl)-, methyl ester; Methyl 2-bromo-6-fluoro-3-trifluoromethylbenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Bromo-6-Fluoro-3-(Trifluoromethyl)Benzoate adheres to stringent quality management protocols. Every batch is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.