Description

2'-Deoxy-2'-Fluoro-N3-[(Pyridin-2-Yl)Methyl]-β-D-Arabinouridine CAS NO 2072145-51-6 is a high-purity, modified nucleoside analog designed for advanced pharmaceutical research and development. This compound is of significant interest for its potential role as a key intermediate or active pharmaceutical ingredient (API) in the development of novel antiviral and anticancer therapeutics. It is primarily targeted at research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in nucleoside-based drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of next-generation antiviral drugs, particularly those targeting RNA viruses.
• Anticancer Drug Research: Investigated as a potential precursor for prodrugs designed to inhibit cancer cell proliferation.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleic acid metabolism and polymerase function.
• Prodrug Development: Acts as a core structure for creating masked prodrugs to improve bioavailability and targeted delivery.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleoside analogs.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	2'-Deoxy-2'-Fluoro-N3-[(Pyridin-2-Yl)Methyl]-β-D-Arabinouridine
CAS No.	2072145-51-6
Molecular Formula	C16H18FN3O5
Molecular Weight	351.33 g/mol
Synonyms	2'-Deoxy-2'-fluoro-N3-(pyridin-2-ylmethyl)-β-D-arabinouridine; 2'-F-N3-Pyridinylmethyl-β-D-arabinouridine; 2'-Fluoro-N3-(2-pyridylmethyl)arabinouridine; 2072145-51-6; N3-[(Pyridin-2-yl)methyl]-2'-deoxy-2'-fluoro-β-D-arabinofuranosyluracil; β-D-Arabinouridine, 2'-deoxy-2'-fluoro-N3-[(2-pyridinyl)methyl]-
EINECS	Contact for details

Quality Control

Every batch of 2'-Deoxy-2'-Fluoro-N3-[(Pyridin-2-Yl)Methyl]-β-D-Arabinouridine is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and MS, to ensure compliance with research and development grade standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.