Description

2,6-Difluoro-3-Methylsulfanyl-Benzoic Acid Methyl Ester is a high-value fluorinated aromatic building block, specifically designed for advanced organic synthesis. Its core value lies in the strategic placement of fluorine and methylthio groups, which are critical for modulating the electronic and steric properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluoro and methylthio motifs enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a specialized building block for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized monomers for advanced polymers with specific optical or electronic properties.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects requiring precise fluorination and functionalization.

Basic Information

Product Name	2,6-Difluoro-3-Methylsulfanyl-Benzoic Acid Methyl Ester
CAS No.	2027537-27-3
Molecular Formula	C9H8F2O2S
Molecular Weight	218.22 g/mol
Synonyms	Methyl 2,6-difluoro-3-(methylthio)benzoate; 2,6-Difluoro-3-(methylthio)benzoic acid methyl ester; Benzoic acid, 2,6-difluoro-3-(methylthio)-, methyl ester; 3-Methylsulfanyl-2,6-difluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Methylsulfanyl-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.