Description

Bulevirtide CAS NO 2012558-47-1 is a synthetic peptide drug substance, representing a significant advancement in antiviral therapeutics. This compound is specifically designed as a first-in-class entry inhibitor, targeting a critical step in the viral lifecycle. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of treatments for chronic hepatitis B and D virus (HBV/HDV) infections. Its targeted mechanism offers a promising approach for patients with limited therapeutic options.

Application

• Active Pharmaceutical Ingredient (API) in antiviral medications for chronic hepatitis B (HBV).
• Key component in formulations targeting hepatitis D virus (HDV) co-infection.
• Reference standard for analytical method development and validation in quality control laboratories.
• Research-grade material for preclinical and clinical studies investigating novel antiviral mechanisms.
• Building block for further chemical modification in medicinal chemistry research programs.
• Process development and scale-up activities within contract development and manufacturing organizations (CDMOs).

Basic Information

Product Name	Bulevirtide
CAS No.	2012558-47-1
Molecular Formula	C215H342N62O63S
Molecular Weight	4811.4 g/mol
Synonyms	Myrcludex B; Hepcludex; HBV/HDV Entry Inhibitor; Bulevirtide acetate; NAFLD-20; GLP-26; NTCP inhibitor; Pre-S1 derived lipopeptide
EINECS	Contact for details

Quality Control

Our Bulevirtide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and safety, meeting the stringent requirements for pharmaceutical active substances. Certificates of Analysis (COA) detailing specifications such as assay, related substances, residual solvents, and microbiological quality are provided with every shipment. We adhere to cGMP guidelines to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Bacterial Endotoxins	< 1.0 EU/mg
Microbial Enumeration	Meets Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.