Description

(R)-(+)-2-Methoxypropionitrile is a high-purity chiral nitrile building block of significant importance in asymmetric synthesis. Its value lies in its utility as a versatile intermediate for constructing complex, optically active molecules, particularly in the pharmaceutical and agrochemical sectors. This product is essential for research chemists and process development scientists in fine chemical and API manufacturing who require a reliable source of enantiomerically pure synthons.

Application

• As a key chiral intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Utilized in asymmetric catalysis and the preparation of chiral ligands for transition metal complexes.
• Building block for the development of novel agrochemicals, such as herbicides and fungicides, with enhanced enantioselective activity.
• Precursor in the synthesis of specialty chemicals and advanced materials requiring specific stereochemistry.
• Used in academic and industrial research for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(R)-(+)-2-Methoxypropionitrile
CAS No.	299396-92-2
Molecular Formula	C4H7NO
Molecular Weight	85.10 g/mol
Synonyms	(R)-2-Methoxypropionitrile; (R)-(+)-2-Methoxypropane nitrile; (R)-2-Methoxypropanenitrile; (R)-α-Methoxypropionitrile; (R)-O-Methyl lactonitrile; (2R)-2-Methoxypropanenitrile; (R)-Methoxyacetonitrile, methyl-; (R)-2-Methoxy-2-methylacetonitrile
EINECS	Contact for details

Quality Control

Our (R)-(+)-2-Methoxypropionitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. For long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.