Description

Bis(3-Aminophenyl) 3,5-Di(Trifluoromethyl)Phenyl Phosphine Oxide is a specialized organophosphorus compound featuring both amine and electron-deficient trifluoromethylphenyl groups. This unique structure makes it a valuable high-performance monomer and intermediate for advanced material synthesis. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key building block for active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and stability.
• Ligand for Catalysis: Functions as a precursor for chiral or electron-deficient phosphine ligands in transition metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• High-Performance Polymer Monomer: Incorporated into polyimides, polyamides, or epoxy resins to impart high thermal stability, flame retardancy, and low dielectric constants for electronic applications.
• Material Science Research: Employed in the development of novel organic electronic materials, such as OLED host materials or charge-transport layers.
• Chemical Synthesis Intermediate: Provides a versatile platform for further functionalization via its amine groups, enabling the creation of dyes, pigments, and other specialty chemicals.

Basic Information

Product Name	Bis(3-Aminophenyl) 3,5-Di(Trifluoromethyl)Phenyl Phosphine Oxide
CAS No.	299176-31-1
Molecular Formula	C26H17F6N2OP
Molecular Weight	518.39 g/mol
Synonyms	3,5-Bis(trifluoromethyl)phenylbis(3-aminophenyl)phosphine oxide; [3,5-Bis(trifluoromethyl)phenyl]bis(3-aminophenyl)phosphine oxide; Bis(3-aminophenyl)[3,5-bis(trifluoromethyl)phenyl]phosphine oxide; 1,1'-(3,5-Bis(trifluoromethyl)phenylphosphoryl)bis(3-aminobenzene); Phosphine oxide, [3,5-bis(trifluoromethyl)phenyl]bis(3-aminophenyl)-
EINECS	Contact for details

Quality Control

Our Bis(3-Aminophenyl) 3,5-Di(Trifluoromethyl)Phenyl Phosphine Oxide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.