Description

13C6 Glucosylsphingosine (D18:1) is a stable isotope-labeled analog of glucosylsphingosine, a key intermediate in glycosphingolipid metabolism. This high-purity compound is essential for precise quantitative analysis in mass spectrometry-based lipidomics and metabolic flux studies. It serves as a critical internal standard for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic sectors, enabling accurate measurement of endogenous glucosylsphingosine levels.

Application

• Mass Spectrometry Internal Standard: Primary use as a quantitative reference standard in LC-MS/MS and GC-MS analysis for biomarker discovery and validation.
• Metabolic Research: Tracing studies in sphingolipid biosynthesis and degradation pathways to understand cellular signaling and disease mechanisms.
• Diagnostic Assay Development: Calibration and quality control in clinical diagnostic kits targeting lysosomal storage disorders, such as Gaucher disease.
• Pharmaceutical R&D: Drug metabolism and pharmacokinetics (DMPK) studies for therapeutics targeting sphingolipid-related pathways.
• Biomarker Quantification: Accurate measurement of glucosylsphingosine in biological fluids (plasma, serum, CSF) for disease monitoring and research.
• Academic Research: Fundamental studies in cell biology, biochemistry, and molecular medicine related to glycosphingolipid function.

Basic Information

Product Name	13C6 Glucosylsphingosine (D18:1)
CAS No.	299172-48-8
Molecular Formula	C30H5813C6NO8
Molecular Weight	~660.8 g/mol (for labeled form)
Synonyms	D-Glucosylsphingosine (D18:1, 13C6); D-Glucosyl-β1-1'-D-erythro-sphingosine (13C6); (2S,3R,4E)-2-Amino-4-octadecen-1,3-diol 1-(β-D-Glucopyranoside) (13C6); Lyso-Gb1 (13C6); Lyso-GL-1 (13C6); GlcSph (13C6); Isotopically Labeled Glucosylceramide Degradation Product; 13C6-Labeled Glucosylsphingosine
EINECS	Contact for details

Quality Control

Every batch of 13C6 Glucosylsphingosine (D18:1) is manufactured and analyzed under strict quality systems to ensure the highest isotopic and chemical purity for research and diagnostic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed data on isotopic enrichment, purity, and identity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥ 95%
Isotopic Enrichment	≥ 99 atom % 13C
Isotopic Purity (MS)	≥ 98%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.