Description

4,5-Dibromo-2-Fluorobenzoic Acid is a high-purity fluorinated and brominated benzoic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique halogenated structure makes it a valuable building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and pesticides, where the fluorine and bromine atoms can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated and brominated aromatic cores essential in electronic materials for displays and lighting.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce halogenated aromatic groups into polymer chains, altering thermal and optical properties.
• Organic Synthesis Building Block: Employed in Suzuki, Buchwald-Hartwig, and other cross-coupling reactions to introduce di-bromo and fluoro substituents regioselectively.
• Chemical Research & Development: A versatile reagent for academic and industrial research in exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	4,5-Dibromo-2-Fluorobenzoic Acid
CAS No.	289039-48-1
Molecular Formula	C7H3Br2FO2
Molecular Weight	297.90 g/mol
Synonyms	2-Fluoro-4,5-dibromobenzoic Acid; 4,5-Dibromo-2-fluorobenzoic Acid; Benzoic acid, 4,5-dibromo-2-fluoro-; 289039-48-1; 4,5-Dibromo-2-fluoro-benzoic acid; 2-Fluoro-4,5-dibromo-benzoic acid
EINECS	Contact for details

Quality Control

Our 4,5-Dibromo-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific batch results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.