Description

D-Alanine-15N is a stable isotope-labeled analog of the non-essential amino acid D-alanine, where the nitrogen atom is enriched with the 15N isotope. This compound is a critical tool for advanced research and analytical applications, providing a distinct mass signature for precise tracking and quantification in complex systems. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, metabolic studies, and nuclear magnetic resonance (NMR) spectroscopy.

Application

• As an internal standard for the accurate quantification of D-alanine in biological samples using mass spectrometry (MS).
• For metabolic pathway tracing and flux analysis in microbiological and biochemical research.
• In the synthesis of isotopically labeled peptides, proteins, and other bioactive compounds for pharmaceutical R&D.
• As a key component in cell culture media for NMR-based metabolomics studies.
• For use in structural biology and protein dynamics studies via NMR spectroscopy.
• In the development and validation of analytical methods for amino acid analysis.
• As a precursor for the synthesis of more complex 15N-labeled fine chemicals and intermediates.

Basic Information

Product Name	D-Alanine-15N
CAS No.	287476-24-8
Molecular Formula	C₃H₇¹⁵NO₂
Molecular Weight	90.08 g/mol (for 15N labeled form)
Synonyms	(2R)-2-Aminopropanoic-15N acid; D-2-Aminopropionic-15N acid; (R)-Alanine-15N; D-α-Alanine-15N; (R)-2-Aminopropanoic-15N acid; D-Alanine (15N); Alanine-15N, D-; D-Ala-15N
EINECS	Contact for details

Quality Control

Our D-Alanine-15N is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and mass spectrometry, to confirm isotopic enrichment, chemical purity, and chiral integrity. Certificates of Analysis (COA) detailing isotopic purity (atom % 15N), chemical purity (by HPLC), and specific optical rotation are provided to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (atom % 15N)	≥ 98%
Optical Rotation [α]²⁰D	-14.0° to -15.0° (c=1 in 1N HCl)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.