Description

3-Hydroxybutyric-4-13C Acid Sodium Salt is a stable, isotopically labeled sodium salt of β-hydroxybutyrate, a key metabolic intermediate. This compound is essential for researchers and manufacturers requiring precise metabolic pathway tracing and quantification in complex biological systems. It is primarily utilized in the pharmaceutical, diagnostic, and life science research sectors for advanced analytical applications.

Application

• Stable Isotope Tracer Studies: Used in metabolic flux analysis (MFA) and pharmacokinetic research to track the fate of carbon atoms in biochemical pathways.
• Internal Standard for Mass Spectrometry: Serves as a critical quantitative standard in LC-MS/MS and GC-MS methods for accurate measurement of endogenous β-hydroxybutyrate levels.
• Diagnostic Kit Manufacturing: Incorporated as a calibrated reference material in clinical diagnostic kits for ketone body detection, enhancing accuracy and reliability.
• Nutritional and Metabolic Research: Applied in studies investigating ketosis, diabetes, starvation, and the effects of specific diets on energy metabolism.
• Pharmaceutical Development: Utilized in the research and quality control of therapeutics targeting metabolic disorders.
• Biochemical Assay Development: Employed as a high-purity substrate or standard in enzymatic assays and other in vitro diagnostic procedures.

Basic Information

Item	Detail
Product Name	3-Hydroxybutyric-4-13C Acid Sodium Salt
CAS No.	287111-43-7
Molecular Formula	C413CH7NaO3
Molecular Weight	128.09 g/mol (approx.)
Synonyms	Sodium 3-Hydroxybutyrate-4-13C; Sodium β-Hydroxybutyrate-4-13C; 3-Hydroxybutanoic-4-13C Acid Sodium Salt; BHB-4-13C Sodium Salt; (R,S)-3-Hydroxybutyric-4-13C Acid Sodium Salt; Ketone Body-13C Sodium Salt; 13C-Labeled Sodium 3-Hydroxybutyrate; 287111-43-7 (CAS)
EINECS	Contact for details

Quality Control

Every batch of our 3-Hydroxybutyric-4-13C Acid Sodium Salt is manufactured and tested under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing specifications for identity, purity (HPLC/NMR), isotopic enrichment, and residual solvents is provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom %
Chemical Purity (NMR)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.