Description

Glyceryl-2-13C Trihexadecanoate is a stable isotope-labeled analog of tripalmitin, where the carbon-13 isotope is specifically incorporated at the sn-2 position of the glycerol backbone. This precise labeling makes it an indispensable internal standard for quantitative mass spectrometry analysis in lipidomics and metabolic research. It is primarily used by analytical laboratories, pharmaceutical R&D departments, and academic institutions conducting advanced studies in lipid metabolism, biomarker discovery, and tracer studies.

Application

• Quantitative Mass Spectrometry (MS) Internal Standard: Serves as a critical reference compound for the accurate quantification of endogenous triglycerides and their metabolites in complex biological samples via LC-MS/MS or GC-MS.
• Lipidomics Research: Enables precise tracking and measurement of triacylglycerol (TAG) species, lipid flux, and metabolic pathways in cell cultures, tissues, and biofluids.
• Stable Isotope Tracer Studies: Used in metabolic flux analysis to investigate the biosynthesis, turnover, and catabolism of neutral lipids in nutritional and disease state models.
• Clinical Diagnostics Development: Supports the development and validation of high-precision clinical assays for dyslipidemia and other metabolic disorders.
• Pharmaceutical Drug Metabolism & Pharmacokinetics (DMPK): Acts as a tracer to study the absorption, distribution, metabolism, and excretion (ADME) of lipid-based drug formulations.
• Food Science & Nutrition Research: Facilitates the analysis of fat content, lipid composition, and metabolic fate of dietary fats in nutritional studies.
• Quality Control & Method Validation: Employed as a certified reference material (CRM) to validate analytical methods and ensure accuracy and reproducibility in testing laboratories.

Basic Information

Product Name	Glyceryl-2-13C Trihexadecanoate
CAS No.	287111-33-5
Molecular Formula	C51H9813CO6
Molecular Weight	~ 807.34 g/mol (for 13C1 isotopologue)
Synonyms	1,3-Dihexadecanoyl-2-[(1-13C)hexadecanoyl]-sn-glycerol; 2-13C-Tripalmitin; [2-13C]Tripalmitin; Glyceryl Trihexadecanoate-2-13C; sn-Glycerol-2-13C-1,2,3-trihexadecanoate; Tripalmitin-2-13C; 1,2,3-Trihexadecanoylglycerol-2-13C; Palmitin-2-13C
EINECS	Contact for details

Quality Control

Our Glyceryl-2-13C Trihexadecanoate is manufactured under strict quality protocols to ensure the highest isotopic and chemical purity for critical research applications. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and high-resolution mass spectrometry to confirm isotopic enrichment, positional specificity, and chemical identity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, storage at 2-8°C is acceptable. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Chemical Purity (HPLC)	≥ 98%
Isotopic Purity (13C)	≥ 99 atom % 13C
Isotopic Enrichment Position	sn-2 position of glycerol
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.