Description

D-Mannose-Ul-13C6 is a uniformly carbon-13 labeled isotopologue of D-Mannose, a naturally occurring monosaccharide. This stable isotope-labeled compound is essential for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway tracing. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic industries for applications in mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy, and metabolic flux analysis.

Application

• Internal Standard for Mass Spectrometry (MS): Provides accurate quantification of D-Mannose in complex biological matrices like plasma, urine, and cell lysates.
• Metabolic Flux Analysis (MFA): Tracks the flow of carbon through metabolic pathways in cell cultures and organisms to study diseases like cancer and diabetes.
• NMR Spectroscopy Studies: Used as a tracer to elucidate metabolic structures and dynamics without radioactive hazards.
• Pharmaceutical R&D: Supports drug metabolism and pharmacokinetics (DMPK) studies for drug candidates targeting carbohydrate metabolism.
• Clinical Diagnostics Development: Aids in creating assays for inborn errors of metabolism related to mannose metabolism.
• Biochemical Research: Investigates glycosylation processes, carbohydrate-protein interactions, and enzyme mechanisms.
• Nutritional Science: Used in tracer studies to understand the absorption and utilization of dietary sugars.

Basic Information

Product Name	D-Mannose-Ul-13C6
CAS No.	287100-74-7
Molecular Formula	¹³C₆H₁₂O₆
Molecular Weight	186.10 g/mol (for ¹³C₆ isotopologue)
Synonyms	D-[U-¹³C₆]Mannose; Mannose-¹³C₆; (3S,4S,5S,6R)-6-(Hydroxymethyl)oxane-2,3,4,5-tetrol-¹³C₆; Uniformly Labeled ¹³C₆ D-Mannose; D-Mannose (U-¹³C₆); Stable Isotope-Labeled D-Mannose; ¹³C₆-Mannose; Mannose (U-¹³C₆, 99%)
EINECS	Contact for details

Quality Control

Our D-Mannose-Ul-13C6 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (Atom % ¹³C), chemical purity by HPLC, and specific optical rotation. We support compliance with relevant standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % ¹³C)	≥ 99%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.