Description

D-[3-13C]Glucose is a stable isotope-labeled analog of D-glucose, specifically enriched with carbon-13 at the C-3 position. This high-purity labeled compound is essential for advanced metabolic research, enabling precise tracking and quantification of glucose utilization and metabolic flux in biological systems. It is a critical reagent for scientists in pharmaceutical development, clinical diagnostics, and nutritional biochemistry who require uncompromised isotopic purity and chemical stability for their tracer studies.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to map and quantify intracellular metabolic pathways in cell cultures, tissues, and whole organisms.
• Drug Mechanism Studies: Employed in pharmaceutical research to investigate how drug candidates alter glucose metabolism in disease models, such as cancer or diabetes.
• Clinical Research & Diagnostics: Serves as a substrate in advanced diagnostic assays and clinical studies to understand metabolic disorders.
• Nutritional Science: Utilized to study carbohydrate metabolism, energy expenditure, and substrate utilization in nutritional and exercise physiology.
• NMR & Mass Spectrometry: Acts as an internal standard or labeled substrate for quantitative analysis using Nuclear Magnetic Resonance (NMR) spectroscopy and Mass Spectrometry (MS).
• Biotechnology & Fermentation: Applied in metabolic engineering to optimize microbial strains for bio-production by analyzing central carbon metabolism.

Basic Information

Product Name	D-[3-13C]Glucose
CAS No.	287100-64-5
Molecular Formula	C6H12O6 (with 13C at position 3)
Molecular Weight	~181.15 g/mol (exact mass depends on enrichment)
Synonyms	D-Glucose-3-13C; (3-13C)Glucose; D-(+)-Glucose-3-13C; 3-13C-Labeled D-glucose; D-Glucose (3-13C); Isotopic D-glucose; 13C-Labeled glucose tracer; D-Glucose-3-13C, 99 atom % 13C
EINECS	Contact for details

Quality Control

Every batch of D-[3-13C]Glucose is manufactured and tested under strict quality systems to ensure the highest isotopic and chemical purity required for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as isotopic enrichment (atom % 13C), chemical purity, and specific optical rotation. Our quality commitment aligns with the standards expected for high-value research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be sealed under an inert atmosphere after opening and desiccated for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (atom % 13C)	≥ 99% (by NMR or MS)
Chemical Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	+52.5° to +53.0° (c=10, H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.