Description

D-Fructose (U-13C6) is a uniformly carbon-13 labeled isotopologue of the natural monosaccharide fructose, with the CAS number 287100-63-4. This high-purity stable isotope-labeled compound is essential for advanced metabolic research, providing a critical tracer for accurate quantification and pathway analysis using techniques like NMR and mass spectrometry. It is primarily utilized by research institutions, pharmaceutical companies, and diagnostic developers in the fields of metabolomics, nutritional studies, and drug development.

Application

• Metabolic Flux Analysis (MFA): As a tracer substrate for studying carbohydrate metabolism, glycolysis, and the pentose phosphate pathway in cell cultures and biological systems.
• Quantitative NMR (qNMR): Serving as an internal standard for the precise quantification of fructose and related metabolites in complex biological matrices.
• Mass Spectrometry (MS): Used in LC-MS and GC-MS based assays to enhance detection sensitivity and accuracy in targeted metabolomics and pharmacokinetic studies.
• Nutritional Research: Investigating fructose absorption, utilization, and its role in metabolic disorders such as diabetes and obesity.
• Pharmaceutical Development: Employed in the development and validation of diagnostic assays and in drug metabolism studies to trace metabolic pathways.
• Biochemical Research: As a tool for enzyme mechanism studies and for probing biochemical reaction networks.

Basic Information

Product Name	D-Fructose (U-13C6)
CAS No.	287100-63-4
Molecular Formula	¹³C₆H₁₂O₆
Molecular Weight	186.10 g/mol (based on ¹³C)
Synonyms	Fructose (U-13C6); D-(-)-Fructose (U-13C6); Levulose (U-13C6); Fruit Sugar (U-13C6); (3S,4R,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one (U-13C6); 13C6-Fructose; Uniformly Labeled 13C-Fructose; [U-13C6]-Fructose
EINECS	Contact for details

Quality Control

Our D-Fructose (U-13C6) is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is characterized by advanced analytical techniques including NMR and HPLC-MS to confirm isotopic enrichment (typically >99 atom % ¹³C) and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (Atom % ¹³C)	≥ 99%
Chemical Purity (HPLC)	≥ 98%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.