Description

1,4-Butanediamine-1,4-13C2, Putrescine-1,4-13C2 is a stable isotope-labeled analog of putrescine, a key biogenic amine and metabolic intermediate. This compound is essential for use as an internal standard in mass spectrometry-based quantitative analysis, ensuring high accuracy and reproducibility in research. It is primarily required by analytical laboratories, pharmaceutical researchers, and metabolomics specialists working in drug development, biomarker discovery, and biochemical pathway analysis.

Application

• Quantitative Mass Spectrometry (MS): Serves as a critical internal standard for the precise quantification of endogenous putrescine levels in complex biological matrices like plasma, urine, and tissue homogenates.
• Metabolomics & Biomarker Research: Enables accurate tracking and measurement of putrescine and related polyamine metabolic fluxes in studies of cancer, cell proliferation, and neurological disorders.
• Pharmaceutical & Pharmacokinetic Studies: Used in drug metabolism and pharmacokinetic (DMPK) studies to quantify drug-induced changes in polyamine pathways.
• Clinical Diagnostics Development: Facilitates the development and validation of robust LC-MS/MS clinical assays for diagnosing conditions associated with polyamine dysregulation.
• Stable Isotope Tracer Studies: Acts as a labeled tracer to elucidate the biosynthesis and catabolism of polyamines in in vitro and in vivo systems.
• Quality Control & Method Validation: Provides a reference standard for validating analytical methods in compliance with guidelines like ICH Q2(R1) in pharmaceutical quality control laboratories.

Basic Information

Product Name	1,4-Butanediamine-1,4-13C2, Putrescine-1,4-13C2
CAS No.	287100-61-2
Molecular Formula	13C2H12N2
Molecular Weight	90.14 g/mol (for labeled form)
Synonyms	Putrescine-1,4-13C2; 1,4-Diaminobutane-1,4-13C2; Tetramethylenediamine-1,4-13C2; Butane-1,4-diamine-1,4-13C2; [1,4-13C2]-Putrescine; 13C2-Labeled Putrescine; Stable Isotope-Labeled Putrescine
EINECS	Contact for details

Quality Control

Every batch of our 1,4-Butanediamine-1,4-13C2 is produced and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity to meet the exacting demands of analytical and research applications. Comprehensive testing includes isotopic enrichment (by NMR or MS), chemical purity (by HPLC), and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (NMR/MS)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (HPLC)	≥ 98%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.