Description

Dl-Lysine-1,2-13C2 Dihydrochloride is a stable isotope-labeled derivative of the essential amino acid lysine, specifically enriched with carbon-13 at the 1 and 2 positions. This compound is a critical tool for advanced research requiring precise metabolic and pharmacokinetic tracing. It is primarily utilized by scientists and quality control professionals in pharmaceutical development, nutritional research, and analytical chemistry. The product is supplied as a high-purity material to ensure reliable and reproducible experimental results.

Application

• Isotope-Labeled Internal Standard for the accurate quantification of lysine in complex biological matrices using LC-MS/MS and GC-MS.
• Metabolic Pathway Tracing in biomedical and nutritional research to study protein synthesis, turnover, and amino acid metabolism.
• Drug Metabolism and Pharmacokinetics (DMPK) studies for the development of new pharmaceutical compounds.
• Proteomics and Biomarker Discovery, serving as a heavy-isotope labeled standard for relative and absolute quantification (SILAC/AQUA).
• Quality Control Reference Material for the calibration of analytical instruments and validation of methods in contract research organizations (CROs) and testing labs.
• Stable Isotope Feeding Studies in agricultural and animal science to investigate feed efficiency and nutrient utilization.

Basic Information

Product Name	Dl-Lysine-1,2-13C2 Dihydrochloride
CAS No.	286437-16-9
Molecular Formula	C413C2H16Cl2N2O2
Molecular Weight	Approx. 223.11 g/mol (Contact for exact isotopic weight)
Synonyms	DL-Lysine-1,2-13C2 dihydrochloride; (RS)-2,6-Diaminohexanoic-1,2-13C2 acid dihydrochloride; Lysine-1,2-13C2 dihydrochloride (DL); 13C2-Lysine dihydrochloride; (±)-Lysine-1,2-13C2 dihydrochloride; H-Lys-OH-1,2-13C2·2HCl; 2,6-Diaminocaproic-1,2-13C2 acid dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of Dl-Lysine-1,2-13C2 Dihydrochloride is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, chiral purity, isotopic enrichment, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C at positions 1 & 2
Chemical Purity (Assay)	≥ 95.0% (on anhydrous basis)
Optical Purity (Chiral HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.