Description

Dl-Phenyl(Alanine-3-13C) CAS NO 286425-42-1 is a stable isotope-labeled analog of the amino acid phenylalanine, where the carbon atom at the 3-position is enriched with the carbon-13 isotope. This compound is a critical tool for advanced research and development, enabling precise metabolic pathway tracing and quantitative analysis in complex biological systems. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and academic research sectors for applications in drug metabolism studies (DMPK), proteomics, and as an internal standard in mass spectrometry.

Application

• As a stable isotope-labeled internal standard for the accurate quantification of phenylalanine and related metabolites in bioanalytical methods using LC-MS/MS and GC-MS.
• For tracer studies in metabolic research, including investigations into phenylalanine metabolism, phenylketonuria (PKU), and amino acid flux analysis.
• In pharmaceutical development for drug metabolism and pharmacokinetic (DMPK) studies to elucidate the metabolic fate of new chemical entities.
• Use in proteomics and protein research for metabolic labeling to study protein synthesis, turnover, and post-translational modifications.
• As a building block for the synthesis of more complex isotope-labeled peptides, proteins, or pharmaceutical intermediates.
• Application in nutritional science research to study amino acid absorption, utilization, and whole-body protein metabolism.
• For NMR spectroscopy as a probe to study molecular structure and dynamics without significant signal interference from natural abundance carbon-13.

Basic Information

Product Name	Dl-Phenyl(Alanine-3-13C)
CAS No.	286425-42-1
Molecular Formula	C9H1113CNO2
Molecular Weight	~166.19 g/mol (for 13C labeled form)
Synonyms	(±)-2-Amino-3-(13C)phenylpropanoic acid; DL-3-(13C)Phenylalanine; DL-Phenylalanine-3-13C; Phenylalanine (3-13C, DL-); (RS)-2-Amino-3-(13C)phenylpropanoic acid; (3-13C)-DL-α-Aminohydrocinnamic acid; DL-α-Amino-β-(13C)phenylpropionic acid
EINECS	Contact for details

Quality Control

Our Dl-Phenyl(Alanine-3-13C) is produced under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of research and analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (atom % 13C), chemical purity (by HPLC), and chiral purity. We adhere to rigorous quality testing protocols, and specifications can be tailored to meet specific project needs upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chiral Purity (DL Ratio)	~50:50 (Racemic mixture)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.