Description

Sodium Butyrate-2-13C is a stable isotope-labeled derivative of sodium butyrate, where the carbon atom at the 2-position is enriched with the 13C isotope. This compound is essential for advanced research requiring precise metabolic and pharmacokinetic tracing, offering unparalleled accuracy in detection and quantification. It is a critical tool for scientists and professionals in pharmaceutical development, nutritional biochemistry, and metabolic research who require reliable, high-purity isotopic standards.

Application

• Isotopic Tracer in Metabolic Studies: Used to investigate the metabolism of short-chain fatty acids (SCFAs) like butyrate in the gut, liver, and other tissues.
• Drug Metabolism and Pharmacokinetics (DMPK): Serves as an internal standard in LC-MS and GC-MS analyses for accurate quantification of butyrate and its metabolites in biological samples.
• Nutritional and Microbiome Research: Employed to trace the production, absorption, and systemic effects of butyrate derived from dietary fiber fermentation by gut microbiota.
• Biochemical Pathway Analysis: Facilitates the detailed mapping of metabolic pathways, including fatty acid oxidation and synthesis.
• Stable Isotope Labeling in Cell Culture: Used in in vitro studies to track the incorporation of butyrate into cellular biomolecules.
• Veterinary and Animal Science Research: Applied in studies on rumen metabolism and animal nutrition to understand SCFA dynamics.

Basic Information

Product Name	Sodium Butyrate-2-13C
CAS No.	286367-62-2
Molecular Formula	C313CH7NaO2
Molecular Weight	112.08 g/mol (for 13C1 labeled form)
Synonyms	Butanoic-2-13C acid, sodium salt; Sodium butanoate-2-13C; [2-13C]-Sodium butyrate; 13C-Labeled sodium butyrate; Isotopic sodium butyrate; Na-Butyrate-2-13C; Sodium n-butyrate-2-13C
EINECS	Contact for details

Quality Control

Our Sodium Butyrate-2-13C is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % 13C), chemical purity (by HPLC/NMR), and identity confirmation. We adhere to rigorous analytical standards to guarantee batch-to-batch consistency and reliability for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (Atom % 13C)	≥ 99%
Chemical Purity (HPLC)	≥ 98%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
pH (5% solution)	7.0 - 9.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.