Description

Uridine-13C9-15N2 5'-(Tetrahydrogen Triphosphate) Sodium Salt is a high-purity, isotopically labeled nucleotide essential for advanced metabolic and biochemical research. This compound serves as a critical internal standard and tracer in quantitative mass spectrometry, enabling precise analysis of RNA synthesis, nucleotide metabolism, and cellular energy pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and CROs specializing in metabolomics, pharmacokinetics, and stable isotope-resolved studies.

Application

• Metabolomics & Flux Analysis: As a stable isotope-labeled tracer for investigating pyrimidine metabolism and nucleotide synthesis pathways in cell cultures and model organisms.
• Mass Spectrometry (LC-MS/MS, GC-MS): Employed as a high-purity internal standard for the accurate quantification of endogenous uridine nucleotides and related metabolites.
• Pharmaceutical R&D: Used in drug discovery to study the mechanism of action of antiviral and anticancer agents targeting nucleotide metabolism.
• Biochemical Assay Development: A key reagent for enzymatic assays involving RNA polymerases, kinases, and other nucleotide-dependent enzymes.
• Nutritional & Diagnostic Research: Applied in studies of mitochondrial function, inborn errors of metabolism, and biomarker discovery.

Basic Information

Product Name	Uridine-13C9-15N2 5'-(Tetrahydrogen Triphosphate) Sodium Salt
CAS No.	285978-18-9
Molecular Formula	C913C9H1415N2O15P3Na4 (or [13C9,15N2]-UTP·Na4)
Molecular Weight	Contact for details
Synonyms	[13C9,15N2]-UTP Sodium Salt; Uridine-5'-triphosphate-13C9,15N2 tetrasodium salt; Isotopically Labeled UTP; (13C9,15N2)UTP; Stable Isotope-Labeled Uridine Triphosphate; UTP-13C9-15N2; [13C9,15N2]Uridine 5'-triphosphate tetrasodium salt
EINECS	Contact for details

Quality Control

Every batch of our isotopically labeled nucleotides is produced and tested under strict quality control protocols to ensure exceptional chemical and isotopic purity for sensitive analytical applications. We provide comprehensive Certificates of Analysis (COA) detailing purity (by HPLC), isotopic enrichment (by MS), and other critical parameters. Our manufacturing process adheres to cGMP guidelines where applicable, supporting traceability and reproducibility for research and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Chemical Purity)
Isotopic Enrichment (MS)	≥ 98 atom % 13C; ≥ 98 atom % 15N
pH (in solution)	6.0 - 8.0
Water Content (KF)	≤ 5.0 %
Biological Activity (Enzymatic)	Conforms (where tested)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.