Description

2-Amino Nevirapine CAS NO 284686-15-3 is a key pharmaceutical intermediate, specifically a derivative of the non-nucleoside reverse transcriptase inhibitor (NNRTI) Nevirapine. This compound is of critical importance for the research and development of novel antiviral agents and for the synthesis of advanced drug candidates targeting HIV and other retroviruses. It is primarily required by pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and fine chemical synthesis specialists focused on antiviral therapeutics.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of Nevirapine analogs and next-generation NNRTIs for antiviral drug development.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production pathway for manufacturing Nevirapine and its derivative APIs.
• Research & Development: Serves as a standard reference compound and a starting material for medicinal chemistry studies in virology and pharmacology.
• Process Chemistry: Employed in scaling up and optimizing synthetic routes for antiviral drugs in pilot plants and commercial manufacturing.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) specializing in high-potency active ingredients (HPAPIs).
• Academic Research: Utilized in university and institutional labs for studying drug resistance mechanisms and developing new therapeutic strategies against HIV.

Basic Information

Product Name	2-Amino Nevirapine
CAS No.	284686-15-3
Molecular Formula	C15H14N6O
Molecular Weight	294.31 g/mol
Synonyms	2-Amino-11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one; 2-Amino-11-cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one; Nevirapine 2-Amino Derivative; 2-Amino Nevirapine Impurity; 2-Amino-NVP; 2-Amino-11-Cyclopropyl-4-Methyl-5H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6(11H)-one
EINECS	Contact for details

Quality Control

Our 2-Amino Nevirapine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) are provided with every shipment, detailing comprehensive specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.