Description

1-[(4R)-4,5-Dihydro-4-Isopropyl-2-Oxazolyl]Isoquinoline is a high-purity chiral oxazoline derivative, a critical building block in advanced organic synthesis. Its value lies in its role as a versatile ligand precursor and intermediate for creating complex, stereoselective molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new therapeutic agents, including potential anticancer and antiviral drugs.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands used in metal-catalyzed asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Intermediate in the synthesis of novel, optically active pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Building block for advanced organic materials, such as liquid crystals or conductive polymers, where specific stereochemistry is required.
• Academic & Process R&D: Used in university and industrial laboratories for methodological development in stereoselective organic transformations.

Basic Information

Product Name	1-[(4R)-4,5-Dihydro-4-Isopropyl-2-Oxazolyl]Isoquinoline
CAS No.	280755-83-1
Molecular Formula	C₁₅H₁₆N₂O
Molecular Weight	240.30 g/mol
Synonyms	(4R)-4-(1-Methylethyl)-4,5-dihydro-2-(isoquinolin-1-yl)-1,3-oxazole; (R)-4-Isopropyl-1-isoquinolin-1-yl-4,5-dihydrooxazole; 1-[(4R)-4,5-Dihydro-4-isopropyl-2-oxazolyl]isoquinoline; (R)-4-Isopropyl-2-(isoquinolin-1-yl)-4,5-dihydrooxazole; Chiral Isoquinoline-Oxazoline Ligand Precursor
EINECS	Contact for details

Quality Control

Our 1-[(4R)-4,5-Dihydro-4-Isopropyl-2-Oxazolyl]Isoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) with full chromatographic data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.