Description

Cyclopentanecarboxylic Acid, 3-Amino-4-Fluoro-, (1R,3S,4S)- (9Ci) is a high-purity, chiral fluorinated cyclopentane derivative of significant interest in advanced pharmaceutical synthesis. This compound matters as a sophisticated building block, offering a unique three-dimensional scaffold with defined stereochemistry and fluorine substitution for modulating the biological activity and metabolic stability of drug candidates. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the research and development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore new chemical space with fluorinated, conformationally constrained analogs.
• Peptidomimetic Development: Serves as a constrained, non-natural amino acid surrogate in the design of peptide mimetics to enhance proteolytic stability and receptor selectivity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective catalytic reactions to construct complex molecular architectures.
• Agrochemical Research: Potential intermediate in the development of new generation herbicides or fungicides with improved efficacy and environmental profile.
• Material Science Precursor: Can be utilized in the synthesis of specialized ligands for catalysis or advanced polymers with unique properties.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 3-Amino-4-Fluoro-, (1R,3S,4S)- (9Ci)
CAS No.	262279-96-9
Molecular Formula	C6H10FNO2
Molecular Weight	147.15 g/mol
Synonyms	(1R,3S,4S)-3-Amino-4-fluorocyclopentanecarboxylic acid; (1R,3S,4S)-3-Amino-4-fluorocyclopentane-1-carboxylic acid; rel-(1R,3S,4S)-3-Amino-4-fluorocyclopentanecarboxylic acid; 3-Amino-4-fluorocyclopentanecarboxylic acid (stereoisomer); Fluorocyclopentane amino acid derivative; Chiral fluorinated cyclopentane carboxylate
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 3-Amino-4-Fluoro-, (1R,3S,4S)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for demanding research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.