Description

2,4-Difluoro-5-(Trifluoromethyl)Benzoic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group, makes it a critical intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including potential drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Organic Electronic Materials: Employed in the synthesis of novel materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Advanced Polymer Modification: Acts as a monomer or modifier to introduce fluorine into polymer chains, enhancing chemical resistance and surface properties.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for exploring new fluorination methodologies and creating complex molecular architectures.

Basic Information

Product Name	2,4-Difluoro-5-(Trifluoromethyl)Benzoic Acid
CAS No.	261945-01-1
Molecular Formula	C8H3F5O2
Molecular Weight	226.10 g/mol
Synonyms	5-(Trifluoromethyl)-2,4-difluorobenzoic Acid; 2,4-Difluoro-5-trifluoromethylbenzoic Acid; 2,4-Difluoro-α,α,α-trifluoro-m-toluic Acid; Benzoic acid, 2,4-difluoro-5-(trifluoromethyl)-; 261945-01-1; 5-Trifluoromethyl-2,4-difluorobenzoic acid
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-5-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent batch-to-batch quality. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.