Description

2-(Di-T-Butylphosphino)-2'-Methylbiphenyl is a specialized organophosphorus ligand widely used in transition metal catalysis. This compound matters for its crucial role in facilitating highly efficient and selective cross-coupling reactions, enabling the synthesis of complex organic molecules. It is primarily needed by manufacturers and R&D teams in the pharmaceutical, agrochemical, and advanced materials industries for process development and production.

Application

• As a key ligand in Buchwald-Hartwig amination reactions for C-N bond formation.
• Catalyst component in Suzuki-Miyaura cross-coupling for biaryl synthesis.
• Facilitates α-arylation of carbonyl compounds and other C-C bond-forming processes.
• Used in the research and production of active pharmaceutical ingredients (APIs) and drug intermediates.
• Employed in the synthesis of agrochemicals and fine chemicals requiring selective catalysis.
• Development of new catalytic systems for academic and industrial research.
• Potential use in materials science for creating specialty polymers and electronic materials.

Basic Information

Product Name	2-(Di-T-Butylphosphino)-2'-Methylbiphenyl
CAS No.	255837-19-5
Molecular Formula	C21H29P
Molecular Weight	312.43 g/mol
Synonyms	2-(Di-tert-Butylphosphino)-2'-methylbiphenyl; 2-Methyl-2'-(di-tert-butylphosphino)biphenyl; DTBM-SPhos; DavePhos; Di-tert-butyl(2'-methyl-[1,1'-biphenyl]-2-yl)phosphine; 2-(Di-tert-butylphosphanyl)-2'-methyl-1,1'-biphenyl; 2-(Bis(1,1-dimethylethyl)phosphino)-2'-methyl[1,1'-biphenyl]
EINECS	Contact for details

Quality Control

Our production of 2-(Di-T-Butylphosphino)-2'-Methylbiphenyl adheres to stringent quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized by NMR, HPLC, and elemental analysis to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C or as specified on the label. This material is hygroscopic and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.