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Rac-2-(Di-T-Butylphosphino)-1,1'-Binaphthyl CAS NO 255836-67-0


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CAS No.:255836-67-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Rac-2-(Di-T-Butylphosphino)-1,1'-Binaphthyl CAS NO 255836-67-0 is a chiral phosphine ligand widely used in asymmetric catalysis. This compound is valued for its ability to induce high enantioselectivity in a variety of transition metal-catalyzed reactions, which is critical for producing optically active intermediates and active pharmaceutical ingredients (APIs). It is an essential tool for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop efficient synthetic routes.

Application

  • As a versatile ligand for asymmetric hydrogenation reactions, crucial for producing chiral amines and alcohols.
  • Catalyst component in asymmetric cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig amination.
  • Key chiral inducer in asymmetric allylic substitution reactions for C-C and C-X bond formation.
  • Use in the synthesis of pharmaceutical intermediates requiring high enantiomeric purity.
  • Research and development of novel homogeneous catalysts for academic and industrial applications.
  • Production of agrochemicals and flavors & fragrances where chirality impacts biological activity or sensory properties.

Basic Information

Product Name Rac-2-(Di-T-Butylphosphino)-1,1'-Binaphthyl
CAS No. 255836-67-0
Molecular Formula C32H35P
Molecular Weight 450.60 g/mol
Synonyms rac-2-(Di-tert-butylphosphino)-1,1'-binaphthyl; (±)-2-(Di-tert-butylphosphino)-1,1'-binaphthyl; rac-DTBNp; rac-2-(Di-t-butylphosphino)-1,1'-binaphthyl; DTBNP (racemic); rac-BINAP-TBu; 1,1'-Binaphthalene-2-yl-di-tert-butylphosphine (racemic); (rac)-DTB-BINAP
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Quality Control

Our Rac-2-(Di-T-Butylphosphino)-1,1'-Binaphthyl is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee batch-to-batch consistency and support your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item Specification
Appearance White to off-white solid
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
31P NMR Purity Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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