Description

2-Acetamido-2-Deoxy-D-[1-13C]Glucose is a stable isotope-labeled derivative of N-acetylglucosamine, where the carbon-1 position is enriched with the 13C isotope. This compound is a critical tool for advanced metabolic research and analytical method development, providing a non-radioactive tracer for precise tracking and quantification. It is essential for researchers and manufacturers in the fields of pharmaceutical development, biochemistry, and mass spectrometry, where understanding metabolic pathways and ensuring accurate analytical results is paramount.

Application

• Metabolic Pathway Tracing: Used as a stable isotope-labeled internal standard in metabolic flux analysis to study glucose and amino sugar metabolism.
• Mass Spectrometry (MS) Quantification: Serves as a critical internal standard for the accurate quantification of N-acetylglucosamine and related metabolites in LC-MS and GC-MS applications.
• Glycobiology Research: Employed in the study of glycosylation processes, glycoprotein synthesis, and carbohydrate-active enzymes.
• Pharmaceutical R&D: Utilized in the development and validation of bioanalytical methods for drug metabolism and pharmacokinetics (DMPK) studies.
• NMR Spectroscopy: Acts as a 13C-labeled substrate for nuclear magnetic resonance studies to elucidate molecular structures and dynamics.
• Diagnostic Reagent Manufacturing: A key component in the production of high-precision diagnostic kits and assays for clinical research.

Basic Information

Product Name	2-Acetamido-2-Deoxy-D-[1-13C]Glucose
CAS No.	253679-94-6
Molecular Formula	C8H15NO6 (with 13C at position 1)
Molecular Weight	~222.2 g/mol (13C adjusted)
Synonyms	N-Acetyl-D-[1-13C]glucosamine; 1-13C-N-Acetylglucosamine; 2-Acetamido-2-deoxy-D-glucose-1-13C; GlcNAc-1-13C; NAG-1-13C; (2R,3R,4R,5S,6R)-2-(Acetylamino)-6-(hydroxymethyl)-1-13C-tetrahydro-2H-pyran-3,4,5-triol
EINECS	Contact for details

Quality Control

Every batch of our 2-Acetamido-2-Deoxy-D-[1-13C]Glucose is manufactured and tested under a strict quality management system. We guarantee high isotopic enrichment and chemical purity to meet the exacting standards of research and analytical applications. Comprehensive Certificates of Analysis (COA) detailing isotopic purity, chemical assay, and impurity profiles are provided to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment (13C at position 1)	≥ 99 atom % 13C
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.