Description

D-Fructose-3-13C is a stable isotope-labeled analog of fructose, a fundamental monosaccharide. This product is essential for advanced research and analytical applications requiring precise metabolic tracing and quantification. It is primarily utilized by scientists and quality control professionals in the pharmaceutical, nutritional science, and biotechnology industries for applications such as metabolic pathway analysis and the development of diagnostic assays.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to study carbohydrate metabolism in cell cultures, tissues, and whole organisms.
• Quantitative NMR (qNMR): Serves as an internal standard for the accurate quantification of fructose and related sugars in complex mixtures.
• Pharmaceutical Research: Employed in the development and validation of bioanalytical methods for drug metabolism and pharmacokinetics (DMPK) studies.
• Nutritional Science Studies: Facilitates research into fructose absorption, utilization, and its role in metabolic disorders.
• Stable Isotope Dilution Mass Spectrometry (IDMS): A critical component for high-precision quantification in clinical diagnostics and food authenticity testing.
• Biochemical Pathway Elucidation: Helps in mapping and understanding specific enzymatic steps in glycolysis and fructolysis.

Basic Information

Product Name	D-Fructose-3-13C
CAS No.	249928-59-4
Molecular Formula	C6H12O6 (with 13C at position 3)
Molecular Weight	181.15 g/mol (approx.)
Synonyms	Fructose-3-13C; [3-13C]-D-Fructose; 13C Labeled Fructose; Levulose-3-13C; (3R,4S,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one-3-13C; D-(-)-Fructose-3-13C; Fruit Sugar-3-13C
EINECS	Contact for details

Quality Control

Our D-Fructose-3-13C is manufactured under strict quality management systems. Each batch is characterized to ensure high chemical and isotopic purity, typically exceeding 99% chemical purity and 99 atom % 13C enrichment. Comprehensive testing includes identification (IR, NMR), assay (HPLC), and specific tests for related substances and residual solvents. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	13C enrichment at position 3 confirmed
Assay (HPLC)	≥ 99.0%
Isotopic Enrichment	≥ 99 atom % 13C
Specific Optical Rotation	-91° to -95° (c=1 in H2O)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.