Description

1,1'-[(1S)-6,6'-Dimethoxy[1,1'-Biphenyl]-2,2'-Diyl]Bis[1,1-Dicyclohexyl-Phosphine is a high-value, chiral bisphosphine ligand of significant importance in asymmetric catalysis. Its core value lies in enabling highly enantioselective transformations, which are critical for the efficient synthesis of single-enantiomer pharmaceutical intermediates and fine chemicals. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical API synthesis.
• Critical component in asymmetric cross-coupling and C-C bond-forming reactions.
• Used in the development of stereoselective catalysts for agrochemical active ingredient production.
• Facilitates enantioselective synthesis of complex natural products and fragrances.
• Employed in academic and industrial R&D for novel catalytic process discovery.
• Applicable in the synthesis of electronic materials and chiral polymers where stereoregularity is key.

Basic Information

Product Name	1,1'-[(1S)-6,6'-Dimethoxy[1,1'-Biphenyl]-2,2'-Diyl]Bis[1,1-Dicyclohexyl-Phosphine
CAS No.	246223-35-8
Molecular Formula	C38H56O2P2
Molecular Weight	606.79 g/mol
Synonyms	(S)-DTBM-SEGPHOS; (S)-6,6'-Dimethoxy-2,2'-bis(dicyclohexylphosphino)biphenyl; (S)-DTBM-SegPhos; (S)-5,5'-Bis(dicyclohexylphosphino)-6,6'-dimethoxy-1,1'-biphenyl; (S)-DTBM-SEGPHOS ligand; (S)-(-)-DTBM-SEGPHOS; 1,1'-[(1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diyl]bis[1,1-dicyclohexylphosphine]; S-DTBM-SEGPHOS
EINECS	Contact for details

Quality Control

Our production of this high-purity chiral ligand adheres to stringent quality protocols. Every batch is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, enantiomeric excess, and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.