Description

Dl-Alanine-3-13C,2-D1 is a stable isotope-labeled analog of the amino acid alanine, specifically enriched with carbon-13 at the 3-position and deuterium at the 2-position. This compound is an essential tool for advanced research in metabolic pathway analysis, protein structure determination, and quantitative mass spectrometry. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and academic research sectors who require high-purity, isotopically labeled standards for precise analytical and diagnostic applications.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to study central carbon metabolism, glycolysis, and amino acid biosynthesis pathways in cell cultures and biological systems.
• Quantitative Proteomics & Mass Spectrometry: Serves as an internal standard for the accurate quantification of alanine and related metabolites via LC-MS/MS and GC-MS techniques.
• NMR Spectroscopy: Employed in nuclear magnetic resonance studies for protein structure elucidation and dynamic studies, leveraging the 13C and 2H (D) labels.
• Pharmaceutical Research: Critical in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules and their metabolites.
• Clinical Diagnostics: Used in the development of advanced diagnostic assays for metabolic disorders.
• Biochemical Research: Acts as a building block for the synthesis of isotopically labeled peptides, proteins, and other complex biomolecules.

Basic Information

Product Name	Dl-Alanine-3-13C,2-D1
CAS No.	244237-64-7
Molecular Formula	C213C1H4D1NO2
Molecular Weight	91.10 g/mol (for 13C1, D1)
Synonyms	(±)-2-Amino(3-13C,2-D)propanoic acid; DL-2-Aminopropionic acid-3-13C,2-D1; Alanine-3-13C,2-D1; DL-α-Alanine-3-13C,2-D1; (RS)-Alanine-3-13C,2-D1; 3-13C,2-D1-DL-Alanine; Racemic Alanine-3-13C,2-D1; 2-Aminopropanoic acid-3-13C,2-D1
EINECS	Contact for details

Quality Control

Our Dl-Alanine-3-13C,2-D1 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (by NMR or MS), chemical purity (by HPLC), and other critical parameters. We adhere to relevant industry standards for stable isotope-labeled compounds, ensuring reliable and reproducible performance in your analytical workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % 13C
Isotopic Enrichment (D)	≥ 98 atom % D
Chemical Purity	≥ 95% (by 1H NMR)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.