Description

2-Diphenylphosphino-2'-(N,n-Dimethylamino)Biphenyl is a sophisticated, bidentate ligand widely recognized for its pivotal role in modern transition metal catalysis. Its unique electronic and steric properties make it exceptionally valuable for facilitating challenging cross-coupling and asymmetric transformations. This compound is a critical reagent for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise control over reaction pathways is paramount.

Application

• As a highly effective ligand in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Buchwald-Hartwig amination, and Negishi couplings.
• Key component in asymmetric catalysis for the synthesis of chiral intermediates in pharmaceutical active ingredients.
• Used in the development of novel organometallic catalysts for C-H activation and other bond-forming processes.
• Essential for academic and industrial R&D focused on methodology development and process chemistry optimization.
• Employed in the synthesis of fine chemicals and specialty materials requiring high selectivity and yield.

Basic Information

Product Name	2-Diphenylphosphino-2'-(N,n-Dimethylamino)Biphenyl
CAS No.	240417-00-9
Molecular Formula	C26H24NP
Molecular Weight	381.45 g/mol
Synonyms	DavePhos; 2-(Dimethylamino)-2'-diphenylphosphinobiphenyl; 2'-(Dimethylamino)-2-(diphenylphosphino)biphenyl; 2-(Diphenylphosphino)-2'-(N,N-dimethylamino)biphenyl; 2-Diphenylphosphino-2'-(dimethylamino)biphenyl; Biphenyl-2-yl(diphenyl)phosphane; [2'-(Dimethylamino)[1,1'-biphenyl]-2-yl]diphenylphosphine
EINECS	Contact for details

Quality Control

Our production of 2-Diphenylphosphino-2'-(N,n-Dimethylamino)Biphenyl adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for catalytic applications. Each lot is characterized by NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be purged with inert gas after each opening to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR	Conforms to structure
31P NMR	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.