Description

3-(Trifluoromethylthio)Phenylacetic Acid is a high-value fluorinated aromatic building block characterized by its phenylacetic acid core and a reactive trifluoromethylthio substituent. This compound matters for its role in introducing lipophilic and electron-withdrawing groups into target molecules, which is critical for modulating the physicochemical and biological properties of advanced intermediates. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in areas targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethylthio group enhances bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated components for high-performance liquid crystal displays (LCDs).
• Organic Electronics: Employed in the development of novel organic semiconductors and charge-transport materials.
• Chemical Research: Acts as a versatile reagent in organic synthesis for introducing the SCF3 moiety into complex molecular architectures.
• Advanced Material Science: Utilized in creating specialized polymers and coatings with unique surface properties.

Basic Information

Product Name	3-(Trifluoromethylthio)Phenylacetic Acid
CAS No.	239080-04-7
Molecular Formula	C9H7F3O2S
Molecular Weight	236.21 g/mol
Synonyms	[3-(Trifluoromethylthio)phenyl]acetic Acid; 2-[3-(Trifluoromethylsulfanyl)phenyl]acetic Acid; α-(3-(Trifluoromethylthio)phenyl)acetic Acid; m-(Trifluoromethylthio)phenylacetic Acid; 3-(Trifluoromethylsulfanyl)benzeneacetic Acid; (3-((Trifluoromethyl)thio)phenyl)acetic Acid; Phenylacetic acid, 3-(trifluoromethylthio)-; CAS 239080-04-7
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethylthio)Phenylacetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its sensitivity to light and organic solvents, handle and store accordingly to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.