Description

(-)-4'-Fluorotartranilic Acid is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its specific stereochemistry and the presence of a fluorine atom, which are critical for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) in medicinal chemistry due to its fluorinated aromatic moiety.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and natural product derivatives.

Basic Information

Product Name	(-)-4'-Fluorotartranilic Acid
CAS No.	238401-54-2
Molecular Formula	C₁₀H₁₀FNO₄
Molecular Weight	227.19 g/mol
Synonyms	(-)-4'-Fluoro-2,3-dihydroxy-N-phenylsuccinanilic Acid; (2R,3R)-4'-Fluorotartranilic Acid; (2R,3R)-2,3-Dihydroxy-4-fluorosuccinanilic Acid; (R,R)-4'-Fluorotartranilic Acid; 4'-Fluoro-(2R,3R)-tartranilic Acid; N-Phenyl-4-fluorotartramic Acid; Fluorotartranilic Acid Enantiomer
EINECS	Contact for details

Quality Control

Our (-)-4'-Fluorotartranilic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.