Description

(R)-3-Methyl-Pyrrolidine Hydrochloride is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. Its value lies in its stereochemically defined pyrrolidine scaffold, which is a privileged structure in medicinal chemistry for constructing bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various drug candidates, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce enantioselectivity.
• Agrochemical Research: Serves as a building block for developing novel, stereospecific pesticides and herbicides.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors.
• Material Science: Potential precursor for chiral ionic liquids or functionalized polymers with specific stereochemical properties.
• Academic & R&D: A valuable reagent for methodological development in organic and medicinal chemistry research laboratories.

Basic Information

Product Name	(R)-3-Methyl-Pyrrolidine Hydrochloride
CAS No.	235093-98-8
Molecular Formula	C5H12ClN
Molecular Weight	121.61 g/mol
Synonyms	(R)-3-Methylpyrrolidine hydrochloride; (R)-3-Methylpyrrolidinium chloride; (3R)-3-Methylpyrrolidine hydrochloride; (R)-N-Methylpyrrolidine-3-amine hydrochloride; Pyrrolidine, 3-methyl-, (3R)-, hydrochloride; (R)-3-MPyrr·HCl
EINECS	Contact for details

Quality Control

Our (R)-3-Methyl-Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment. We adhere to cGMP principles where applicable to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.